either lost to follow-up or died and were excluded from the analysis
of adenoma and advanced-lesion occurrence. The median
follow-up of all participants was approximately 33 months.
APACC included a 4-year examination and thus had the longest
median follow-up (47.2 months vs 32.2, 31.3, and 37.5 months for
AFPPS, CALGB 9270, and ukCAP, respectively). Follow-up duration
and rate of colonoscopic follow-up were well balanced across
the treatment groups ( Supplementary Table 1 , available online).