3.5. VH:CD ratios in the small intestine of PEDV-inoculated nursing
piglets vs. weaned pigs
To investigate the severity of atrophic enteritis in inoculated
pigs, jejunal VH:CD ratios of all inoculated pigs were measured and
compared with those of uninoculated negative control pigs at each
time-point. Mean (
SDM) jejunal VH:CD ratios of uninoculated
nursing piglets were 8.7 (
1.4) at PID 1 (10 days of age), 7.6 (
1.2)
at PID 3 (12 days of age), and 7.1 (
1.1) at PID 5 (14 days of age). On
the other hand, mean (
SDM) jejunal VH:CD ratios of inoculated nursing piglets were 1.4 (
0.5) at PID 1 (10 days of age), 1.2 (
0.5)
at PID 3 (12 days of age), and 1.1 (
0.6) at PID 5 (14 days of age). At
PIDs 1–5, VH:CD ratios in PEDV-inoculated nursing pigs were
significantly lower than those in uninoculated nursing pigs
(P < 0.01 at each-time point) (Fig. 5A).
 
3.5. VH:CD ratios in the small intestine of PEDV-inoculated nursingpiglets vs. weaned pigsTo investigate the severity of atrophic enteritis in inoculatedpigs, jejunal VH:CD ratios of all inoculated pigs were measured andcompared with those of uninoculated negative control pigs at eachtime-point. Mean (SDM) jejunal VH:CD ratios of uninoculatednursing piglets were 8.7 (1.4) at PID 1 (10 days of age), 7.6 (1.2)at PID 3 (12 days of age), and 7.1 (1.1) at PID 5 (14 days of age). Onthe other hand, mean (SDM) jejunal VH:CD ratios of inoculated nursing piglets were 1.4 (0.5) at PID 1 (10 days of age), 1.2 (0.5)at PID 3 (12 days of age), and 1.1 (0.6) at PID 5 (14 days of age). AtPIDs 1–5, VH:CD ratios in PEDV-inoculated nursing pigs weresignificantly lower than those in uninoculated nursing pigs(P < 0.01 at each-time point) (Fig. 5A).
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