Abstract Plantago ovata Forsk. (isabgol) is a valuable medicinal plant; its seeds and shell have a
significant role in pharmacy as a laxative compound. Increasing soil contamination with cadmium
(Cd) is one of the major concerns and is responsible for toxic effects in plants. This investigation
was aimed to analyze the role of biofertilizers in alleviation of cadmium stress, given at the rate
of 0, 50, and 100 mg kg1 of soil. The plants of isabgol, were grown in pots with and without application
of AM fungi and Azotobacter (alone and combination). Cadmium showed negative effect on
growth and biochemical component whereas proline and MDA content increase with increasing
cadmium concentration. Addition of bio-fertilizer showed better growth and higher pigment concentration
under cadmium stress as compared to the control. The dual inoculation of AM fungi
and Azotobacter was found to be the best in reduction of cadmium stress and promotion of growth
parameters