Due to the strong criticism of the early
clinical studies (for example, small numbers of
participants, lack of baseline examinations, etc.),
Stephen et al. (8, 9) initiated in Glasgow, in 1976,
a double blind clinical trial on 4 ½ and 5 ½ year
old schoolchildren. The group of test children
consumed 200 ml milk each school day (about 200
days per year), containing 1.5 mg fluoride, while
the control group received plain milk. The results