When the humans first came to Tyria, the charr were already there. All its lands were their hunting grounds, all its creatures their prey. The humans drove the charr northward to found their kingdoms, and resisted them when they sought to regain their lands.
At the time, the charr were a unified under their primus imperator, the Khan-Ur. A united charr stood a chance against the humans, however when the Khan-Ur was assassinated without leaving any clear heir, the race fractured into the four High Legions, each led by a cub of the Khan-Ur. Several charr have since held the title of Khan-Ur, however none have been able to unify the charr for longer than a few weeks, each being overthrown or dying in battle shortly after pressing their claim.
In time, the charr began blame the power of the Old Gods for the humans' victories. This led the the charr to seek for gods to call their own, and when the Flame Legion Burnt warband encountered the titans at the volcano Hrangmer, they had found them. The Shamans of the Flame Legion decided that they would accept the magic of the titans, and when the Flame Legion returned, so, too, did the Shamans of the other Legions. The Shamans, in particular those of the Flame Legion, became a ruling caste, and before long the charr were unified once more under their banners. One charr, however, spoke out against the titans - Bathea Havocbringer. She led an underground rebellion against the Shamans, but failed and became a sacrifice to the new gods. Her actions also led to the removal of female charr from the battlefield, and being consigned to domestic duties.
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Once more united, the charr finally resumed the war against the humans in 1070 AE, in a war known to humans as the Charr Invasion. They struck without warning and with a devastating new power, granted to them by the titans. Using the Cauldron of Cataclysm, they brought forth the Searing, destroying the Great Northern Wall and invaded the three human kingdoms: Ascalon, Kryta, and Orr. Ascalon was crushed, but the newly-formed White Mantle were able to prevent the charr from taking Kryta, and the Cataclysm brought the war in Orr to an end for humans and charr alike.