In total, 11 studies of randomised trials had been
included in our meta-analyses. Five studies assessed the
treatment effect for EO healing, of which, one study
compared dexlansoprazole with lansoprazole33 and four
studies compared esomeprazole with lansoprazole.
9, 25, 38, 57 There were four studies that assessed the
treatment efficacy in maintaining healed EO. Among
them, two studies compared dexlansoprazole with placebo28,
32 and two studies compared esomeprazole with
placebo.10, 37 There were two studies that assessed the
effectiveness of short-term treatment for NERD; one
study compared dexlansoprazole with placebo26 and the
other one compared esomeprazole with placebo.31