The BPH group showed a significant increase in serum DHT
level (345 ± 8.17 pg/mL, P < 0.01) compared with the control
group (159 ± 8.34 pg/mL; Fig. 1). In contrast, the
finasteride-treated group showed a significantly reduced serum
DHT level (250.57 ± 25.68 pg/mL, P < 0.01) compared with
the BPH group. Similarly to finasteride-treated group, the
KH053-treated groups showed significant reduction in DHT
levels (249.86 ± 35.07 pg/mL in the 200 mg/kg group,
P < 0.05) compared with the BPH group