French and colleagues summarized the results of four RCTs of manual therapy for persons with hip or knee OA and focused on its impact on pain reliefand function Three of the four trials included patients with knee OA. Only one study examined long-term outcomes. One study compared manual therapy with no treatment, another compared manual therapy with placebo, and two used a comparison group. Theauthors noted the high risk of bias in three of the four studies and suggested with caution that manual therapy might yield better results than exercise for persons with OA.