Effect of AP on NO production in LPS stimulated J774A.1 murine
macrophages. Cells were incubated with LPS (5g/mL) and indicated concentrations
of AP for 24 h. The nitrite content of culture media was analyzed by the Griess
reaction assay and expressed as a percentage of the control (LPS alone). Data are represented
as mean±S.E.M. values. **P < 0.01 compared with the LPS alone. (B) Effect
of AP on PGE2 production in LPS stimulated J774A.1 murine macrophages. Cells were
pretreated with indicated concentrations of AP for 1 h, and then stimulated with LPS
(5g/mL) for 24 h. The PGE2 levels were markedly decreased dose-dependently by
AP and the values are expressed as a percentage of the control (LPS alone). Data are
represented as mean±S.E.M. **P < 0.01 compared with the LPS alone.