The lacquer spraying method was successfully employed for
the fabricating paper-based devices. This spraying method is an
alternative method due to its ease of use, affordability and
simplicity. In addition, there is no requirement for complicated
and expensive instruments or organic solvents. The iron mask was
used to create the pattern of hydrophilic area and hydrophobic
area was obtained by spraying with lacquer. The spraying method
does not suffer from problems of interference from residues remaining in the hydrophilic area after fabrication. Moreover, the paper-based devices were shown to be useful for electrochemical detection methods, and were applied for the determination of nickel in real samples. Therefore, to fabricate paper-based devices,the spraying method with lacquer is one of the effective promising method.