The changes in total phenolics, total anthocyanins,
gallic acid (GA), and 3,4-dihydroxybenzoic acid (DHBA)
contents during black raspberry (BR, Rubus coreanus)
wine manufacturing were investigated. Total phenolic content
gradually increased during BR wine manufacturing. The
total anthocyanin content slightly increased, but the
changes were not significant. The GA and DHBA in BR
wine were detected as main compounds and their content
greatly increased during manufacturing. The DPPH radicalscavenging
activity was also increased during BR wine
manufacturing. In particular, the antioxidant activity in the
blood plasma of rats administered with BR wine concentrate
was significantly higher than those administered with BR
fruit extracts in inhibition of copper ion-induced cholesteryl
ester hydroperoxide formation. These results indicate that
an increase in antioxidant activity of BR wine may be due
to low molecular phenolic compounds including GA and
DHBA produced during the manufacturing.