The possibility of enhancing reactor performance under periodic operation for the ethanol dehydra- tion over -alumina was studied in a laboratory fixed bed reactor [11]. Highly active TiO2 / -Al2 O3 catalysts have been successfully applied for the bioethanol to ethylene dehydration in a microchan- nel reactor [12]. However, there are few reports about the reactor and process design for ethylene production from bioethanol on a large scale [1,13].