As for the cordycepin production by C. militaris,
the liquid surface culture,
the submerged culture ,
and the combination of submerged and static cultures
were investigated to effi-ciently produce cordycepin.
Recently, an efficientmethod to extract
cordycepin from the waste mushroom beds was proposed.
In order to improve cordycepin production to a commercial level,
a novel mutant was obtained from C. militaris using high-energy proton
beam irradiation as reported in our previous study