Suturemediated closure devices tie off the femoral artery with sutures. Collagen plugs seal the puncture site by stimulating platelet aggregation and the release of coagulation factors, which results in the formation of a clot. Extravascular clips or staples are used to seal off the puncture site in the artery. Hemostasis is usually obtained shortly after deployment, allowing the patient to get out of bed and ambulate faster