Abstract
Therapy-related myelodysplastic syndrome and therapy-related acute myelocytic leukemia (AML) are now recognized as
hematologic malignancies that occur a few years after chemotherapy for primary malignancy with alkylating agents or topoisomerase
II inhibitors. The secondary leukemia is usually AML and sometimes is preceded by a myelodysplastic syndrome.
Acute lymphoblastic leukemia (ALL) as a secondary leukemia is quite rare, and secondary T-cell ALL after AML is even
rarer.We report a case of a 56-year-old woman who developed T-cell ALL after a 3-year remission of AML (M2).We thought
that this case would be extremely valuable for studying the etiology and biological characteristics of T-cell ALL as a secondary
leukemia after AML. Int J Hematol. 2003;77:518-521.
©2003 The Japanese Society of Hematology