Avila-Funes, Melno-Carranza, Helene Payette, and Amieva(2007) demonstrated that the presence of depressive symptoms is a risk factor for the development of impairment in instrumental DLA. However, this risk was not observed for basic life activities. Functional impairment is multifactor, starts and develops in an insidious way and manifests in a jerarquic order. As a consequence, instrumental DLA are affected in the first place followed by basic life activities.