vasoconstriction may severely restrict peripheral microcirculation
leading to hypoperfusion. Continuous application of vasopressors
decreases the rate of oxygen delivered by arteriolar vessels, increases
the rate of oxygen release to the microcirculation, and reduces tissue
PO2, including the muscle. This, in turn, may result in a hampering of a
muscle contraction. This is in accordance with our results because the
nonresponders had more vasopressors administered