Calculate the quantity of each ingredient for the amount to be prepared. Accurately weigh or measure each ingredient. Heat the propylene glycol to 70°C to 80°C. Add the piroxicam and dexpanthenol; mix well. Add the ethanol and Pluronic F127; mix well. Add about 25 mL of the water as hot water (70°C), adjust the pH with trolamine to about 7, and add the remaining water to the final weight of 100 g. Cool to room temperature and allow the bubbles to escape. Adjust the pH to about 8; then package and label. - See more at: http://www.uspharmacist.com/content/c/41434/?t=autoimmune_disorders,men%27s_health#sthash.Ni753zuR.dpuf