Ferrets (Mustela putorius furo) are susceptible to several respiratory
pathogens, such as SARS-CoV and influenza A virus. Upon IT
and IN inoculation of ferrets with 106 TCID50 of HCoV-EMC/2012,
viral RNA was only detected in nasal and oropharyngeal swabs
up to 2 dpi, and not in the 12 days thereafter. No infectious virus
was detected, and none of the animals seroconverted (Raj et al.,
2014b).