Albendazole is the medication of choice to treat multiple diseases caused by parasites from the nematode and cestode types, among which there are alveolar echinococcosis and neurocysticercosis. Additionally, it has been successfully implemented as alternative therapy in other parasitosis, without generating clinically relevant adverse effects. The drug binds to the B-tubulin of the parasitic cell and impedes microtubule polymerization, which interferes with the mitotolic spindle formation and the glucose uptake; it also inhibits mitochondrial fumarate reductase which alters oxidative phosphorylation and the parasite’s energy metabolism, this produces the cell’s immobility, spastic paralysis, and-finally-death.