Cannabinoids include THC (tetrahydrocannabinol), hashish and marijuana. Due to high addiction potential and risk of abuse, cannabinoids are not ideally indicated as therapeutic pain killers. According to the 2008 reports of U.S. Department of Health and Human Services, almost 15.2 million individuals (over 12 years of age) are actively involved in marijuana consumption. Long term consumption for recreational purposes is associated with deficits in coordination, memory and intellect. Besides the highest abuse potential, hallucinogens are also associated with the highest risk of side effects and much severe withdrawal symptoms and toxicities.