Because of the impossibility of employing the developed
FIA titration in aqueous micellar medium in analysis of
medicinal forms in the form of coated tablets, FIA titration
with perchloric acid in anhydrous acetic acid medium
were developed as a flow-through variant of the batch titration determination of phenothiazines as described in official
methods. The non-aqueous medium eliminates the effect
of the auxiliary substances. The results of the determination
of the phenothiazine derivatives in practical samples by the
FIA titration in non-aqueous medium agree with the results
obtained by official batch titration. The developed FIA in
non-aqueous medium reduces the time of titration and decreases
the disadvantages of work with corrosive acetic acid
medium.