). First, a screening test was carried out to determine the sensibility of each microorganism to spent coffee and coffee brew samples. Next, the lowest amount of extract capable of inhibiting microorganism growth was estimated. Finally, the antimicrobial effect of spent coffee extracts was measured at 24, 48 and 72 hours of exposure. The inhibition diameters of the agar-well diffusion method (Table 4) showed that all the tested samples were more active