Most studies interested in strengthening or resistance exercises, including the study of Anderson et al, and Zebis et al. They emphasized that strengthening exercises and specific resistance training of the shoulder, arm, and hand muscles for office workers can relieve musculoskeletal pain symptoms in several regions of the upper body, as well as neck/ shoulder symptoms. However, our interest was the effect of stretching exercises and we can demonstrate that stretching exercise can relieve pain, improve neck functions, and quality of life (physical dimension of Short Form-36). herefore, the better combination should be stretching exercise during an acute to sub-acute phase of musculoskeletal pain, followed by strengthening exercise when pain subsides, in order to gain maximal benefits from these exercises.