The burden of malaria in the SEA Region is still high; it is second to Sub-Saharan Africa: – around 1.32 billion people are at risk of malaria – most cases are among the productive age groups, mainly the poor and vulnerable populations (e.g. migrant workers, subsistence farmers, ethnic communities) – in 2010, the reported cases and deaths due to malaria were 2.4 million and 2426, respectively; WHO estimated that there were 28 million cases and 38 000 deaths due to malaria.