A significant difference was also detected when com- paring our population with that from Japan forRHCEE/e. In Brazilian Japanese descendants theRHCEEEgenotype frequencies were 4.30%, lower than to the population from Japan (9.4%) and similar to the Brazilian mixed popu- lation (2%).
The distribution ofRHCECandRHCEEallele and genotype frequencies in Brazilian Japanese descendants indicate a possible influence of the mixed Brazilian popula- tion in descendants and gene flow.