In the Amazon region there are large amounts of wood and agricultural residues whose potential has been underestimated. In the timber industry, raw material waste can be as high as 60%. In the agricultural industry there is no data on how much waste their activities produce. Vianez and Barbosa (2003), suggest several alternatives for the use of wood residues, including the use for the cultivation of edible mushrooms. This activity could contribute to a sustainable regional development.In this way, the objective of this study is to study the feasibility of using sawdust supplemented with soy bran for growing L. strigosus, a native mushroom of the Amazon region.