Shigellosis is usually treated with antibiotics. Antibiotics commonly used for treatment in serious cases are ampicillin, trimethoprim/sufamethoxazole, nalidixic acid, or ciprofloxacin. Antibiotics are only used in serious infections due to the rise in antibiotic resistance of some strains. Mildly infected usually receive no antibiotic treatment and recover quickly. Anti-diarrhea medications such as Imodium or Lomotil should be avoided and are likely to make the illness much worse. There are no vaccines to prevent Shigellosis. However the spread of Shigella from person to person can be stopped by improving hygiene conditions such as washing hands with soap, proper disposal of soiled diapers, sanitation of changing areas, and good judgment on the quality of food and water consumed.