into Cancer and Nutrition food frequency questionnaire,
validated in the InCHIANTI population.29 Educational
level was recorded as years of school. Cognitive function
was evaluated using the Mini-Mental State Examination,
with the total score adjusted for educational level and
age.30 Depressive symptoms were measured using the 20-
item Center for Epidemiologic Studies Depression Scale.
Participants with a score of 16 or more were considered to
be depressed.31 Total leisure time energy expenditure of
physical activity was expressed in metabolic equivalents
using a modified version of a standard questionnaire