However,these methods require expensive instrumentation,
and sample preparation is not available in clinical
laboratories. Methods for the assay of terbutaline
in pharmaceutical dosage forms are usually based
on spectrophotometric determinations [10,11]. A
flow injection analysis method with spectrophoto-metric detection has also been developed for the
colorimetric determination of the drug [12]. The
USA Pharmacopeia [13] recommends a spec-trophotometric method with 4-aminoantipyrine
and ferricyanide, whereas the British Pharmaco-poeia [14] describes an HPLC method for the
determination of terbutaline in drug formulations.
Standard terbutaline can also be determined using
the non-aqueous titrimetric method of both phar-macopeias [13,14]. In recent years, capillary zone
electrophoresis has been applied to determine the
compound in pharmaceutical formulations [15]
and biological fluids [16]