Experimental studies: Several animal studies were identified which suggest that A. paniculata may have contraceptive or antifertility effects following long-term treatment at high doses [26], [27], [28]. However, there is a large degree of discrepancy in the results, with some studies [29], [30] demonstrating no untoward effects even at doses 1000 times those used therapeutically, possibly due to the type of extracts used and the techniques employed to detect change. More work is needed in this area, but the evidence to date suggests that A. paniculata should not be taken during pregnancy or by men or women attempting to achieve conception.