A mixture of 100 g (0.36 mol) 6of sodium phenytoin
anhydrate (SPA), 400 mL of toluene, and 6.6 mL (0.37 mol)
of Water Was stirred rapidly under ambient conditions. After
2 days, about 1 mL of the slurry Was? filtered, and the
resulting solid Was found, by XRPD analysis (13-day
turnaround), to consist of a mixture of SPA and sodium
phenytoin monohydrate (SPM).