The space-time version of the epidemic type aftershock sequence (ETAS) model is based on the empirical
laws for aftershocks, and constructed with a certain space-time function for earthquake clustering. For more
accurate seismic prediction, we modify it to deal with not only anisotropic clustering but also regionally distinct
characteristics of seismicity. The former needs a quasi-real-time cluster analysis that identifies the aftershock
centroids and correlation coefficient of a cluster distribution. The latter needs the space-time ETAS model with
location dependent parameters. Together with the Gutenberg-Richter’s magnitude-frequency law with locationdependent
b-values, the elaborated model is applied for short-term, intermediate-term and long-term forecasting
of baseline seismic activity.