The present study is a co-relational research that investigated the portion of hardiness and social support on anticipating life satisfaction in patients with breast cancer. The population of this study was all patients who were referred to Shohaday-e Tajrish in 1391. Sample consisted of 400 patients selected purposefully. Three questionnaires including hardiness, social support and life satisfaction were administered for assessment of variables. Findings showed a significant correlation between three variables (P