Finally, a further multivariate regression analysis regarding the change in quality of life from baseline to 12 months showed that HD significantly improved by 4.86 points (P = 0.0285) compared to PD on quality of social interaction. For patient satisfaction, PD patients improved by 4.85 points (P = 0.0275) compared to HD patients from baseline to 12 months. There was no other significant influence of dialysis modality on the other HRQoL domains.