Besides Gentianaceae, Guttiferae and Anacardiaceae, the family Clusiaceae also one of the families which produced secondary metabolites, xanthones (Peres and Nagem, 1996; Peres et al., 2000). Garcinia mangostana L. (Clusiaceae) commonly known as mangosteen can be found in the region of Southeast Asia. The fruit and pericarp of G. mangostana have been used as a traditional medicine in Southeast Asia for treatment of diarrhea, dysentery, inflammation and ulcers