Alternatives to the testing of null hypotheses and the reporting of P-values tend to focus on the estimation of parameters of interest and their associated measures of variability. The use of confidence interval estimation or Bayesian inference have been suggested as superior approaches (Cherry 1996). Possibly the most compelling alternative is the use of information theoretic approaches,which use model building and selection, coupled with intimate knowledge of the biological system of interest, to estimate parameters and their variances (Burnham and Anderson 1998). The questions then focus on the values of parameters of interest, confidence in the estimates, and how estimates vary among the populations of interest. Before any of these approaches are practiced, however, the establishment of clear questions and research hypotheses, rather than null hypotheses, is essential.