Throughout our lifetime, our DNA is coding for the manufacture
of small molecules called proteins. These proteins provide
the structure and function for nearly all of life’s biological processes.
Enzymes that facilitate our cells’ chemistry, hormones
that affect our body’s growth and regulation, and antibodies
that form our immune response are all examples of proteins in
action. Just about everything in our bodies – from the color of
our eyes, to carrying oxygen in our blood, to whether we can
digest milk – is determined by the proteins we make.
Once produced within the body, proteins will naturally fold
into a particular shape. This natural form of a protein molecule
is what allows for its specific function. Put simply,
when proteins are folded properly, they work as they should,
and we enjoy relatively good health. When proteins are misfolded,
it affects our body’s ability to function, and problems
may arise over time.
Misfolded proteins can be produced because of genetic
causes, or because of other factors related to chronic inflammation
or increasing age. Regardless, our bodies are
usually capable of identifying and removing these abnormal
proteins. In some cases, though, we either produce too
much of the abnormal proteins for our body to handle, or we
are not able to break down and clean up the proteins at all.
Such defects in protein production and processing are associated
with many diseases.
Throughout our lifetime, our DNA is coding for the manufactureof small molecules called proteins. These proteins providethe structure and function for nearly all of life’s biological processes.Enzymes that facilitate our cells’ chemistry, hormonesthat affect our body’s growth and regulation, and antibodiesthat form our immune response are all examples of proteins inaction. Just about everything in our bodies – from the color ofour eyes, to carrying oxygen in our blood, to whether we candigest milk – is determined by the proteins we make.Once produced within the body, proteins will naturally foldinto a particular shape. This natural form of a protein moleculeis what allows for its specific function. Put simply,when proteins are folded properly, they work as they should,and we enjoy relatively good health. When proteins are misfolded,it affects our body’s ability to function, and problemsmay arise over time.Misfolded proteins can be produced because of geneticcauses, or because of other factors related to chronic inflammationor increasing age. Regardless, our bodies areusually capable of identifying and removing these abnormalproteins. In some cases, though, we either produce toomuch of the abnormal proteins for our body to handle, or weare not able to break down and clean up the proteins at all.Such defects in protein production and processing are associatedwith many diseases.
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