In 2012, an estimated 627,000 people died of malaria—most were young children in sub-Saharan Africa. Within the last decade, increasing numbers of partners and resources have rapidly increased malaria control efforts. This scale-up of interventions has saved 3.3 million lives globally and cut malaria mortality by 45%, leading to hopes and plans for elimination and ultimately eradication. CDC brings its technical expertise to support these efforts with its collaborative work in many malaria-endemic countries and regions.