In this study, some mechanical and physical performance characteristics of three-layer, rubberwood kenaf particleboards were evaluated. The MOE of Type 1 panels was 56% and 79% higher than those of the single-layer panels made from kenaf stem and core particles, respectively. The three-layer particleboards manifested a significant increment in elasticity. Increasing the ratios of RW particles in the surface layer increased the strengths of the resultant panels. Based on these findings, it is concluded that the three-layer rubberwood–kenaf particleboards comprising up to 30% of KS with 10% UF resin are the ideal panels.