Regeneration of tissues using cells, scaffolds and appropriate growth factors is a key approach in the treatments
of tissue or organ failure. Silk protein fibroin can be effectively used as a scaffolding material in
these treatments. Silk fibers are obtained from diverse sources such as spiders, silkworms, scorpions, mites
and flies. Among them, silk of silkworms is a good source for the development of biomedical device. It possesses
good biocompatibility, suitable mechanical properties and is produced in bulk in the textile sector.
The unique combination of elasticity and strength along with mammalian cell compatibility makes silk fibroin
an attractive material for tissue engineering. The present article discusses the processing of silk fibroin into
different forms of biomaterials followed by their uses in regeneration of different tissues. Applications of silk
for engineering of bone, vascular, neural, skin, cartilage, ligaments, tendons, cardiac, ocular, and bladder tissues
are discussed. The advantages and limitations of silk systems as scaffolding materials in the context of
biocompatibility, biodegradability and tissue specific requirements are also critically reviewed.
Regeneration of tissues using cells, scaffolds and appropriate growth factors is a key approach in the treatments
of tissue or organ failure. Silk protein fibroin can be effectively used as a scaffolding material in
these treatments. Silk fibers are obtained from diverse sources such as spiders, silkworms, scorpions, mites
and flies. Among them, silk of silkworms is a good source for the development of biomedical device. It possesses
good biocompatibility, suitable mechanical properties and is produced in bulk in the textile sector.
The unique combination of elasticity and strength along with mammalian cell compatibility makes silk fibroin
an attractive material for tissue engineering. The present article discusses the processing of silk fibroin into
different forms of biomaterials followed by their uses in regeneration of different tissues. Applications of silk
for engineering of bone, vascular, neural, skin, cartilage, ligaments, tendons, cardiac, ocular, and bladder tissues
are discussed.ข้อดีและข้อจำกัดของระบบนั่งร้านผ้าไหมเป็นวัสดุในบริบทของ
การรวมตัวกัน ของตัวเพียงย่อยสลายทางชีวภาพและเนื้อเยื่อเฉพาะความต้องการยังมีความดู
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