Cluster 1 (LE) includes fatigue and weakness.
The concurrence of these two symptoms is consistent
with the results of a previous study;9 they
represent similar meanings in Taiwanese cancer
patients.19 The cluster 2 (poor intake) includes
symptoms of the anorexia-cachexia syndrome,
which has been thought to be mediated by
proinflammatory cytokines, such as interleukin-
1, interleukin-6 and tumor necrosis factoralpha
(TNF-a).20 Cluster 3 (AD) includes the
symptoms that may result from AD, which has
been documented in cancer.21 The paraneoplastic
processes may be one of the causes of
AD.22 Cluster 4 (AI) includes nausea, vomiting,
abdominal fullness, and dyspnea. The apparent
tendency of some gastrointestinal symptoms to
occur together was also noted in a previous
study.23 Dyspnea occurred together with nausea
or vomiting, suggesting that ascites may be an
important contributing factor.24 Cluster 5 is
a PC affecting various sites, which is a special
symptom in advanced cancer patients. Our previous
studies showed that pain in advanced cancer
patients possesses some characteristics,
including being a controllable symptom, and
is frequently linked with depression.6,19 Thus,
pain was separated as an independent symptom
in the process of factor analysis.
Cluster 1 (LE) includes fatigue and weakness.
The concurrence of these two symptoms is consistent
with the results of a previous study;9 they
represent similar meanings in Taiwanese cancer
patients.19 The cluster 2 (poor intake) includes
symptoms of the anorexia-cachexia syndrome,
which has been thought to be mediated by
proinflammatory cytokines, such as interleukin-
1, interleukin-6 and tumor necrosis factoralpha
(TNF-a).20 Cluster 3 (AD) includes the
symptoms that may result from AD, which has
been documented in cancer.21 The paraneoplastic
processes may be one of the causes of
AD.22 Cluster 4 (AI) includes nausea, vomiting,
abdominal fullness, and dyspnea. The apparent
tendency of some gastrointestinal symptoms to
occur together was also noted in a previous
study.23 Dyspnea occurred together with nausea
or vomiting, suggesting that ascites may be an
important contributing factor.24 Cluster 5 is
a PC affecting various sites, which is a special
symptom in advanced cancer patients. Our previous
studies showed that pain in advanced cancer
patients possesses some characteristics,
including being a controllable symptom, and
is frequently linked with depression.6,19 Thus,
pain was separated as an independent symptom
in the process of factor analysis.
การแปล กรุณารอสักครู่..