Results
During the study period, nine of the 36 study
subjects (six of those undergoing training and
three of the control subjects) had their treatment
altered. Seven were changed from inhaled
sodium cromoglycate to an inhaled steroid and
two patients had,/the dose of inhaled steroid
increased. Anthropometric data, blood cholesterol
and lipoproteins values, and lung function
data for the control and training groups are
summarised in table 1. No significant difference
in any of the pre-study measurements
between the two groups was detected by univariate
or multivariate analysis. There was an
improvement in mean (SD) FEV1 (pretreatment
and post-treatment) in both groups
after the study period, which was significant
(p < 0 01) in the training group. There was no
significant difference between the mean change
in FEV, of 0 38 (0-48) litres in the training
group and 0 19 (0 53) litres in the control
group. There was also no difference when
change in FEV1 was expressed as a percentage
of the predicted normal value. Histamine PC20
was unchanged for the two groups.