Protecting against cancer and aging, improving circulation and wound healing, and reducing inflammation and collagen breakdown. It is also used for diabetes and retinopathy. Grape seed is promoted for use in atherosclerosis and peripheral vascular disease, claiming to improve pain relief, limb heaviness, and swelling in circulatory conditions, and to reduce heart attack and stroke. It may have other uses as well. Check with your pharmacist for more details regarding the particular brand you use.