3.1. Resistance of wine LAB strains to gastrointestinal tract
conditions
An important step towards the selection of potential probiotic
candidates is to evaluate their resistance to the extreme conditions
of the GI tract. The first barrier that must be overcome is the
mouth, with a high concentration of lysozyme in the human
saliva; then the stomach, with low pH and digestive enzymes (i.e.
pepsin); and the upper intestine, which contains bile