Other things about the person which may effect drug dangers include:
If they have physical health problems like heart disease, high blood pressure, epilepsy, diabetes, asthma or liver problems, drug use could be more dangerous and possibly make their health problem worse.
The drug users energy levels at the time of consuming drugs can also be important. If they are tired at the time of use then it may have a different or more extreme effect than if they are fresh and full of energy.
If the user has a low body weight the same amount of drugs may effect them more than heavier people. Also people who have eating disorders like anorexia or bulimia can find that drug use makes their eating difficulties even worse.
Males and females can experience drugs in different ways. This is both because of their different physical make up and the different way people view male and female drug use. On average women are of smaller body weight than men, have smaller livers as a proportion of body weight and a greater proportion of body fat. This means that, generally speaking, the same amount of drugs will have a greater effect on a woman than on a man. Obviously this will not apply with a much larger than average woman or a much smaller than average man.
The effects and risks of drug use are also influenced by attitudes towards men and women taking drugs. Women are often seen as doubly bad if they take drugs. Male drug use is often seen as more acceptable than that of women and mothers, in particular, come in for a lot of criticism if they use drugs. Male drug users who are parents are not usually seen in the same sort of way. Sexism can also affect the experience of drug use and drug risks.