In any case, the decision is mainly based on the patient’s
own values and wills. Several modalities have been developed
for promoting advance directives, either very general -
avoid prolonging life through futile treatments -, or more
precise, according to the specific clinical condition (e.g. avoid
tracheostomy and respiratory mechanical support in case of
worsening of ALS) [10]. Also a designed surrogate might help
making a medical decision which could fit with the patient’s