The skin will start to get dry
around 3–4 weeks after treatment
starts. Flaking and scaling of the
skin occurs due to the decreasing
ability of the basal layer to replace
surface layers, shedding of the
epidermis, and reduced skin
lubrication from damage to the
sweat and sebaceous glands.
When new cell proliferation
occurs before desquamation, the
resulting imbalance between cell
production and cell loss results in
dry desquamation (Figure 2).