One limiting step in an enzyme based biorefinery process is
the fast, complete hydrolysis of the cellulose to monomeric sugars,
which can be subsequently converted to a wide range of fuels,
chemicals and biomaterials . To improve the hydrolytic efficiency
of cellulase enzyme preparations, considerable attempts have traditionally focused on their component cellulases because cellulose is the most abundant polysaccharide constituent in lignocellulose. However, it is now recognized that it is necessary to achieve an efficient enzymatic co-hydrolysis of the cellulose and hemicellulose present in pretreated lignocellulosic substrates to fermentable sugars, which requires a supplementation of the cellulases
with some accessory enzymes