Plants are well known source of pharmaceuticals but due to its low yield .It is not economically feasible. On the other hand sacrifice endangered plants for secondary metabolites may distinct these valuable species. To combat these obstacles in vitro tissue culture is a promising tool to get these metabolites. Even in in vitro culture applying other strategies viz. like media manipulation,Phytohormone regulation, precursor feeding,plant cell immobilization,biotransformation and bioconversion etc can be used to obtain good yield of secondary metabolites in tissue culture.Among all these elicitation of tissue culture has been found to be more economical beneficial.